Principal 6 Fertility is a revolutionary fertility supplement. Created by Dr. Hodges, Principal 6 Fertility is a comprehensive formulation based on years of scientific research in reproductive medicine. The ingredients are consistent with ACOG recommendations (American Congress of Obstetricians and Gynecologists) and data specifically investigating ways to improve IVF (in vitro fertilization) success rates.
We based our fertility supplement and prenatal vitamin on the clinical guidelines of ACOG (the American Congress of Obstetricians and Gynecologists), the Mayo Clinic, and the most current reproductive and fertility research. Below are preconception / pregnancy recommendations from ACOG and the Mayo Clinic and how they compare to all of the ingredients in Principal 6 Fertility Supplement and Principal 6 Prenatal Vitamin.
How Our Ingredients Compare to Recommendations from ACOG and the Mayo Clinic
Research Data for the Ingredients of Principal 6 Fertility Supplement
Has been shown to have improved embryo quality (particularly in women with poor ovarian reserves) & Have higher live birth rates
- A. Wiser*, O. Gonen, Y. Ghetler, T. Shavit, A. Berkovitz and A. Shulman. Addition of dehydroepiandrosterone (DHEA) for poor-responder patients before and during IVF treatment improves the pregnancy rate: A randomized prospective study. Hum. Reprod. (2010) 25 (10): 2496-2500.
- David Barad and Norbert Gleicher. Effect of dehydroepiandrosterone on oocyte and embryo yields, embryo grade and cell number in IVF. Hum. Reprod. (2006) 21 (11): 2845-2849.
- David Barad, Hyama Brill, Norbert Gleicher. Update on the use of dehydroepiandrosterone supplementation among women with diminished ovarian function. Journal of Assisted Reproduction and Genetics . December 2007, Volume 24, Issue 12, pp 629-634
Improves Ovarian response & CoQ10 supplementation improves semen quality with beneficial effect on pregnancy rate
- E. Burstein, A. Perumalsamy, Y. Bentov, N. Esfandiari, A. Jurisicova, R.F. Casper. Co-enzyme Q10 supplementation improves ovarian response and mitochondrial function in aged mice. Fertility and Sterility, Volume 92, Issue 3, Supplement, Page S31, September 2009
- Mohammad Reza Safarinejad. The effect of coenzyme Q10 supplementation on partner pregnancy rate in infertile men with idiopathic oligoasthenoteratozoospermia: an open-label prospective study. International Urology and Nephrology, June 2012, Volume 44, Issue 3, pp 689-700
Helps support ovulatory function & Improves quality of eggs
- E. Papaleo, V. Unfer , J.P. Baillargeon, T.T. Chiu. Contribution of myo-inositol to reproduction. European Journal of Obstetrics & Gynecology and Reproductive Biology, Volume 147, Issue 2 , Pages 120-123, December 2009
Though the recommendation for pregnancy is 400-600mcg of folate/folic acid, this is the minimal amount needed to prevent birth defects. But 800-1200 mcg of tetrahydrofolate is best.
Vitamin D3 and Krill Oil
Anti-oxidant properties to help with ovulatory function & improved IVF and pregnancy success
- Sebiha Ozkan, M.D.a, Sangita Jindal, Ph.D.b,, Keri Greenseid, M.D.b, Jun Shu, M.D.c, Gohar Zeitlian, M.D.b, Cheryl Hickmon, B.S.b, Lubna Pal, M.B., B.S. Replete vitamin D stores predict reproductive success following in vitro fertilization. Fertility and Sterility, Volume 94, Issue 4, September 2010, Pages 1314–1319